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Cancer Treatment Reviews 
Volume 29, Issue 6 , December 2003, Pages 533-540 

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doi:10.1016/S0305-7372(03)00105-1     Cite or link using doi   
Copyright  2003 Elsevier Ltd. All rights reserved. 
ANTI-TUMOUR TREATMENT 
The management of brain metastases 
Roy A. Patchell,  

Division of Neurosurgery, University of Kentucky Medical Center, Lexington, KY 
40536, USA 

Available online 4 June 2003. 



Abstract
Brain metastases are neoplasms that originate in tissues outside the brain and 
then spread secondarily to the brain. Metastases to the brain are the most 
common intracranial tumours in adults. Substantial progress has been made in the 
treatment of these tumours, and radiotherapy, surgery, and stereotactic 
radiosurgery are now established treatments. With aggressive treatment, most 
patients experience meaningful symptom reduction and extension of life. 
 
Corresponding author. Correspondence to: Roy A. Patchell MD, Chief of 
Neuro-Oncology, Division of Neurosurgery, University of Kentucky Medical Center, 
800 Rose Street, Lexington, KY 40536 



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      Cancer Treatment Reviews 
      Volume 29, Issue 6 , December 2003, Pages 533-540 


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